Mackenzie grew up in Northern Virginia where she fell in love with lacrosse playing at Centreville High School. She began her college career at Slippery Rock University, a Division II school outside of Pittsburgh. She completed her competitive lacrosse career at George Mason University, where she received a B.S. in Public Health. Mackenzie has coached at Centreville HS, and as lacrosse camp counselor for various programs. She continues to compete in post-collegiate leagues, has two dogs, and lives in Washington, DC where she works in launching technology solutions for clinical trails.